Pipeline
All drug candidates are derived from NuclearPharm’s internal R&D initiatives. Our most advanced, NP-DCM-075, is currently translating from preclinical stages into Phase I clinical trials for the detection of Sentinel Lymph Nodes. NuclearPharm is actively seeking sponsorship to support the ongoing development and successful clinical introduction of these innovative agents.
How NuclearPharm Can Help You
Services
How Can We Help…
At NuclearPharm, we provide expert consulting across all stages of radiopharmaceutical development—from early-stage R&D to preclinical support, process optimization, and clinical translation. Our goal is to streamline your development pipeline, ensure regulatory success, and foster strategic collaborations with academia, industry, and healthcare providers.
We drive the discovery and development of novel drug candidates to address unmet medical needs, with expertise in:
Library Design – Strategic compound selection for targeted applications
Synthesis & Characterization – Organic/inorganic chemistry, IR, NMR, X-ray
Target Identification – Biological targets such as PARP, PSMA, and FAP
We provide expert radiochemistry services, optimizing labeling strategies, automation, and formulation for a wide range of radionuclides, including:
18F, 68Ga, 99mTc, 177Lu, 64Cu, 225Ac, 131I, etc.
Radiolabeling assays for small compounds, peptides, antibodies, etc.
Stability, formulation, lipophilicity, and optimization
Ensuring precision and quality in radiopharmaceuticals through:
TLC & HPLC Method Development – Assessing Quality, Radiochemical Purity (RCP), Radiochemical Yield (RCY), and Molar Activity (Am)
Quality Assurance – Enhancing reliability with radio-TLC and radio-HPLC
Bridging discovery to clinical application with:
Preclinical Study Design – Optimized in vitro and in vivo evaluation
Animal & Oncology Models – Supporting biodistribution and efficacy studies
Custom Proof-of-Concept Studies – Feasibility and research design
Ensuring seamless preclinical-to-clinical transition through:
Process Validation – Reproducibility and regulatory compliance
Automated Radiopharmaceutical Production – Enhancing manufacturing efficiency
We offer rapid troubleshooting and operational optimization for:
Synthesizers – FastLab 1 & 2, Trasis AllInOne
Cyclotrons – Siemens and GE systems for improved efficiency and compliance
Accelerating approvals and advancing technology with:
Regulatory Support – Streamlining SOPs, deviations, CAPA, and documentation
Innovation Consulting – Cutting-edge solutions to advance your facility
Partnership Development – Connecting with academia, clinics, and industry
Grant Applications & Financing – Securing funding for research initiatives
Meet Our Core Team
Antonio Shegani
CEO | Co-Founder
Nektarios Pirmettis
Head of R&D | Co-Founder
Partners & Clients
Partners & Client Testimonials
Our office location
Leof. Andrea Siggrou 196, Athina, 176 71, Greece